PRECISION ONCOLOGY FOR RET-RELATED TUMORS

Precision oncology for RET-related tumors

Aberrant activation of the RET proto-oncogene is implicated in a plethora of cancers.RET gain-of-function point mutations are driver events in multiple endocrine neoplasia 2 (MEN2) syndrome and in sporadic medullary thyroid cancer, while RET rearrangements are driver events in several non-medullary thyroid cancers.Drugs able to inhibit RET have bee

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Legendary islands or phantom islands: in the search of mythical lands in old folk tales, on historical maps and in weather phenomena on open sea

What is the meaning of legendary or phantom islands? A phantom island is a purposed island which was included on maps for a period of time, but was Clothing - Junior Bottoms - Shorts later found not to exist.Most of these phantom islands appeared on maps from the 1200s until the early 1800s.Some of islands did not disappear on maps until our time.B

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